Journal: Journal of Experimental & Clinical Cancer Research : CR
Article Title: MiR-423-5p is a metabolic and growth tuner in hepatocellular carcinoma via MALAT-1 and mitochondrial interaction
doi: 10.1186/s13046-025-03524-2
Figure Lengend Snippet: Figure 7. A Hep3B-LUC control and miR-423-5p overexpressing cells were injected in the liver of NOD SCID mice. Tumor growth was monitored using the IVIS imaging system 200 series (PerkinElmer). Representative images of mice analysed at days of cells injection (Day 1) and a different times (9, 16). Data were acquired and analysed using the Living Image Software version 4.3. B Quantitative analyses of bioluminescence signals in the liver were shown. Luminescent signals are expressed as mean of total flux of photons/sec/cm2/steradian (p/s/cm2/sr). Error bars represent SD. p -values were calculated using an unpaired two-tailed t-test; * \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p<0.05$$\end{document} p < 0.05 . C Representative images ex-vivo of Hep3B-LUC control and miR-423-5p tumors in the liver. * \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p < 0.05$$\end{document} p < 0.05
Article Snippet: Real time tumor growth was monitored weekly using the IVIS Lumina II CCD camera system (PerkinElmer, Shelton, Connecticut, USA) by intraperitoneal injection with 150 mg/Kg D-Luciferin (PerkinElmer).
Techniques: Control, Injection, Imaging, Software, Two Tailed Test, Ex Vivo
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![Figure 7. A Hep3B-LUC control and miR-423-5p overexpressing cells were injected in the liver of NOD SCID mice. Tumor growth was monitored using the <t>IVIS</t> imaging system 200 series (PerkinElmer). Representative images of mice analysed at days of cells injection (Day 1) and a different times (9, 16). Data were acquired and analysed using the Living Image Software version 4.3. B Quantitative analyses of bioluminescence signals in the liver were shown. Luminescent signals are expressed as mean of total flux of photons/sec/cm2/steradian (p/s/cm2/sr). Error bars represent SD. p -values were calculated using an unpaired two-tailed t-test; * \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p<0.05$$\end{document} p < 0.05 . C Representative images ex-vivo of Hep3B-LUC control and miR-423-5p tumors in the liver. * \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p < 0.05$$\end{document} p < 0.05](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_7375/pmc12487375/pmc12487375__13046_2025_3524_Fig7_HTML.jpg)
![Figure 8 A Hep3B-LUC cells were injected in the liver of NOD SCID mice. Mice were treated intraperitoneally (ip) with antisense LNA negative control at 25 mg/Kg twice a week for five treatments and with antisense LNA GapmeR-MALAT-1 at 25 mg/Kg twice a week for five treatment. Real-time tumor growth was monitored using the IVIS imaging system 200 series (PerkinElmer). Representative images of mice analysed before starting the treatment (day 0) and at different times (days 16, 24) were shown. Data were acquired and analysed using the Living Image Software version 4.3. B Quantitative analyses of bioluminescence signals in the liver were shown. Luminescent signals are expressed as mean of total flux of photons/sec/cm2/steradian (p/s/cm2/sr). Error bars represent SD. p -values were calculated using an unpaired two-tailed t-test; * \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p < 0.05$$\end{document} p < 0.05 , ** p -value \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$< 0.01$$\end{document} < 0.01](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_7375/pmc12487375/pmc12487375__13046_2025_3524_Fig8_HTML.jpg)